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Chapter 10: Sampling Distributions and the Central Limit Theorem

drug 1 and drug 2, say, for the reduction of migraine headache levels. One

way of doing this, is to select a group of people who suffer from migraine

headaches at approximately the same pain level, and randomly divide into

two groups. These groups can then be treated with the two different drugs

over a period of time, and the effectiveness of the drugs for these two groups

can be determined.

In the preceding illustration, we may consider the two approximate

homogenous groups as samples from two different independent populations

who were treated with the two drugs. Information obtained about the time it

takes for the pain to reduce to a certain level can then be used to make

comparisons concerning the average times it took for the pain to reduce to

the given specified level for the two drugs.

A general sampling situation is shown in

Figure 10-30

.

Figure 10-30:

Sampling Representation to Investigate the

Sampling Distribution for Two Sample Means

Figure 10-30

shows two populations, denoted as 1 and 2, from which

respective samples of sizes

and

are obtained. The respective sample

means are

̅

and

̅

and the standard deviations are

and

. Each

population has its respective mean denoted by

and

and standard

deviation

and

. Assume that these populations are normally distributed.

We can use the difference between the two sample means as a point estimate

for the difference between the population means. That is, we will let

̅

1

-

̅

2

represents the point estimate for

-

. We can then investigate the

sampling distribution

of

̅

1

-

̅

2

by taking repeated samples from the two